UNC-CH Center for Bioinformatics

Vector NTI

Vector NTI Advance 10 has recently been released by Invitrogen. The latest version available is 10.3. This version contains an enhanced capability for ordering primers from your Explorer Database and the Gateway Cloning function has been improved to allow constructions using the MultiSite Gateway vectors; otherwise it is similar to the earlier 10.x versions.

The modules that make up the Vector NTI system support annotation, assembly, blast searching, translation, primer design, in silico cloning, and a number of other common tools. The graphical interface, image quality, and ease of information import and export from the Vector NTI system are very user friendly.

Vector NTI Advance includes the following programs:

  • Vector NTI - for sequence analysis and data management
  • Align X - for generation of multiple sequence alignments of proteins and nucleic acids
  • ContigExpress - for editing and assembly of sequence chromatograms
  • GenomBench - for viewing genome scale data located on distributed annotation server (DAS) systems
  • BioAnnotator - for physicochemical analyses of nucleic acid and protein sequences
  • Explorer Database – data management and storage

 

Vector NTI Advance 10 is available only from Invitrogen at the following website: (https://commerce.invitrogen.com/index.cfm?fuseaction=userGroup.home&cid=fl-vectornticommunity). It cannot be downloaded from any Center for Bioinformatics website. Invitrogen is offering a static license to any academic/non-profit user which allows an individual to perform installations of Vector NTI on three computers. The license is free but the user is responsible for renewing this license every year with Invitrogen. The license must be renewed each year or the software will go into demo mode. This means that the user cannot perform any operations on molecules.

When it is near time to renew your license, Invitrogen will send you an email reminder. You will not be able to renew the license until it actually expires. Once this occurs the renewal function is enabled (through the “Request a License” link). Once you have renewed, you will be able to re-register your computer through the License Center tab in the Vector NTI User Community. You will receive a new License Key and Registration Number which will have to be applied to your License Manager as outlined below under “Download and Install”. Invitrogen also offers an Installation and Licensing Guide to help you through this process on the Vector NTI User Community main page in the eSupport section.

The Center for Bioinformatics will not be offering Vector NTI 9 (or Vector NTI 7.1 for Macs) any longer for installation. Those currently using Vector NTI 8 or 9 on the dynamic license can keep this or upgrade to Vector NTI 10. The static license can be applied to machines with version 9.x. Vector NTI 10 is available only for PCs, the free version of Vector NTI for Macs available from Invitrogen remains version 7.1; this is identical to the version 7.1 that we were making available through a dynamic license. It is important to note that Vector NTI 7.1 will work only on Mac OS 10.2 and 10.3; version 7.1 will not work with Mac OS 10.4 (Tiger). Vector NTI 10.3 will work on the new Windows Vista OS.

We will continue to support Vector NTI 9 and 10 with workshops and training sessions which can be found at: http://bioinformatics.unc.edu/education/workshops.htm

Instructions on upgrading to Vector 10 can be found at the Invitrogen site above or you can follow the synopsis located on the Shared Bioinformatics Resource website linked below:

How to Download and Install

Vector NTI Frequently Asked Questions (FAQ)